The San Diego Padres handled the Minnesota Twins 6-2 on Friday, August 21, at Petco Park, getting seven sharp innings from Randy Vásquez and a decisive three-run home run from Ty France to cruise to a four-run victory. Fernando Tatis Jr. led the offense with three hits, Manny Machado and Luis Rengifo each added two-hit performances, and Mason Miller slammed the door with a three-strikeout ninth to finish what turned into a clean, complete team win in the 2026 regular season.

Randy Vásquez Delivers Seven Innings of Two-Run Ball

Vásquez was the story on the mound. The right-hander worked all seven innings, surrendering just two earned runs on two hits while walking nobody and punching out three. That kind of efficiency — zero walks across seven frames against a major-league lineup — gave the Padres bullpen exactly the cushion it needed. Vásquez earned the win, and it's hard to argue with how he got it.

The back end of the bullpen was just as tidy. Bradgley Rodriguez threw a scoreless eighth, allowing no hits and striking out one. Then Miller came on for the ninth and was simply electric — three up, three down, all on strikeouts, no hits, no walks. That's the kind of finishing sequence that makes a 6-2 lead feel like 10-2.

Ty France Home Run and Tatis Headline Padres Offense

On the offensive side, the Padres did their damage against Twins starter Connor Prielipp, who allowed six earned runs on eight hits over six innings. San Diego was patient and productive, with four batters recording multi-hit games or significant run production.

  • Ty France: 1-for-1 with a three-run home run and 3 RBI — the turning-point swing of the game
  • Fernando Tatis Jr.: 3-for-4 with 1 RBI — relentless at the plate all night
  • Manny Machado: 2-for-4 with 1 RBI — steady and productive in the middle of the order
  • Luis Rengifo: 2-for-4 with 1 RBI — contributed up and down the lineup

France's home run was the turning point. With Prielipp already having allowed hits to Tatis and others, France's three-run blast gave San Diego a cushion that Vásquez never relinquished. From that moment forward, this one felt settled.

Prielipp Takes the Loss for Minnesota

Prielipp had the strikeouts — seven across six innings — but the hit and run totals against him told the real story. Eight hits and six earned runs is a rough line, and the Padres capitalized efficiently, scoring enough to make the late innings a formality. Travis Adams and Taylor Rogers finished for Minnesota in relief, with Rogers striking out two in a scoreless ninth, but the damage was already done long before that.

What's Next for the Padres

San Diego remains at Petco Park to continue its series against Minnesota. With Vásquez delivering the kind of start that keeps a rotation humming and the offense spreading hits throughout the lineup, the Padres will look to carry that momentum into the next game. A full, clean win like this one — starter goes deep, bullpen closes it out, multiple lineup contributors — is exactly the kind of performance a team wants heading into the next night's first pitch.